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CERTaIN: CER/PCOR Methods: Introduction

Learn the fundamentals of comparative effectiveness research (CER) and patient-centered outcomes research (PCOR) methods and data analysis strategies.

There is one session available:

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Starts Jan 14
Ends Jun 30
Estimated 3 weeks
1–2 hours per week
Progress at your own speed
Optional upgrade available

About this course

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In this course, you will be introduced to basic statistics and study designs used in CER/PCOR and the ethical considerations to take into account when conducting CER/PCOR.

This introductorycourse includes 4 lectures:

  1. Basic Statistics for PCOR/CER I
  2. Basic Statistics for PCOR/CER II
  3. Ethics
  4. Introduction to Comparative Effectiveness and Patient-Centered Outcomes Research

This course is intended for anyone interested in CER/ PCOR methods.

This course is supported by grant number R25HS023214 from the Agency for Healthcare Research and Quality.

At a glance

What you'll learn

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  • Describe basic statistical methods used for CER/PCOR
  • List ethical considerations for CER/PCOR
  • Define CER/PCOR and describe examples of each

Basic Statistics for PCOR/CER I

  • Sampling methods
  • Stratification and controlling for bias and confounding
  • Study power
  • Sample size
  • Common study designs

Basic Statistics for PCOR/CER II

  • Types of data
  • Parametric and non-parametric measures
  • Relationship between sample size and standard deviation
  • Odds ratios and relative risks
  • P-values and confidence intervals


  • Seven principles of research ethics and their application to CER/PCOR
  • History of ethics in research

Introduction to Comparative Effectiveness and Patient-Centered Outcomes Research

  • Examples of CER/PCOR
  • CER vs. randomized controlled trials
  • Patient-centered outcomes Research Institute (PCORI)

About the instructors

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